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1

Panepophenanthrin, from a Mushroom Strain, a Novel Inhibitor of the Ubiquitin-Activating Enzyme

Sekizawa, Ryuichi, Ikeno, Souichi, Nakamura, Hikaru, Naganawa, Hiroshi, Matsui, Susumu, Iinuma, Hironobu, Takeuchi, Tomio

Journal:

Journal of Natural Products

Year:

2002

Language:

english

File:

PDF, 72 KB

english, 2002

2

Ultrasound-guided ilioinguinal/iliohypogastric block did not reduce emergence delirium after ambulatory pediatric inguinal hernia repair: a prospective randomized double-blind study

Ohashi, Nobuko, Denda, Sadahei, Furutani, Kenta, Yoshida, Takayuki, Kamiya, Yoshinori, Komura, Reiko, Nishimaki, Hironobu, Iinuma, Yasushi, Hirayama, Yutaka, Naitou, Shinichi, Nitta, Koju, Baba, Hiros

Journal:

Year:

2016

Language:

english

File:

PDF, 567 KB

english, 2016

3

Biological activities of cyclophellitol.

ATSUMI, SONOKO, IINUMA, HIRONOBU, NOSAKA, CHISATO, UMEZAWA, KAZUO

Journal:

The Journal of Antibiotics

Year:

1990

Language:

english

File:

PDF, 518 KB

english, 1990

4

Production, isolation and structure determination of a novel .BETA.-glucosidase inhibitor, cyclophellitol, from Phellinus sp.

ATSUMI, SONOKO, UMEZAWA, KAZUO, IINUMA, HIRONOBU, NAGANAWA, HIROSHI, NAKAMURA, HIKARU, IITAKA, YOICHI, TAKEUCHI, TOMIO

Journal:

The Journal of Antibiotics

Year:

1990

Language:

english

File:

PDF, 270 KB

english, 1990

5

ChemInform Abstract: Synthesis of Antirheumatic Agent Epoxyquinomicin B.

Naoki Matsumoto, Hironobu Iinuma, Tsutomu Sawa, Tomio Takeuchi

Journal:

Year:

1999

File:

PDF, 29 KB

1999

6

ChemInform Abstract: Diperamycin, a New Antimicrobial Antibiotic Produced by Streptomyces griseoaurantiacus MK393-AF2. Part 1. Taxonomy, Fermentation, Isolation, Physico-Chemical Properties, and Biological Activities.

Naoki Matsumoto, Isao Momose, Maya Umekita, Naoko Kinoshita, Makoto Chino, Hironobu Iinuma, Tsutomu Sawa, Masa Hamada, Tomio Takeuchi

Journal:

Year:

1999

File:

PDF, 27 KB

1999

7

ChemInform Abstract: Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4. Part 1. Taxonomy, Fermentation, Isolation, Physico-chemical Properties, and Biological Activities.

Naoki Matsumoto, Toshio Tsuchida, Masato Maruyama, Naoko Kinoshita, Yoshiko Homma, Hironobu Iinuma, Tsutomu Sawa, Masa Hamada, Tomio Takeuchi, Naohiko Heida, et al. et al.

Journal:

Year:

1999

File:

PDF, 28 KB

1999

8

ChemInform Abstract: Decatromicins A and B, New Antibiotics Produced by Actinomadura sp. MK73-NF4. Part 1. Taxonomy, Isolation, Physico-Chemical Properties, and Biological Activities.

Isao Momose, Hironobu Iinuma, Naoko Kinoshita, Yohko Momose, Setsuko Kunimoto, Masa Hamada, Tomio Takeuchi

Journal:

Year:

2000

File:

PDF, 26 KB

2000

9

ChemInform Abstract: Decatromicins A and B, New Antibiotics Produced by Actinomadura sp. MK73-NF4. Part 2. Structure Determination.

Isao Momose, Sehei Hirosawa, Hikaru Nakamura, Hiroshi Naganawa, Hironobu Iinuma, Daishiro Ikeda, Tomio Takeuchi

Journal:

Year:

2000

File:

PDF, 28 KB

2000

10

ChemInform Abstract: Melleolides K, L, and M, New Melleolides from Armillariella mellea.

Isao Momose, Ryuichi Sekizawa, Nobuo Hosokawa, Hironobu Iinuma, Susumu Matsui, Hikaru Nakamura, Hiroshi Naganawa, Hasa Hamada, Tomio Takeuchi

Journal:

Year:

2000

File:

PDF, 29 KB

2000

11

ChemInform Abstract: New Triene-ansamycins, Thiazinotrienomycins F and G and a Diene-ansamycin, Benzoxazomycin.

Nobuo Hosokawa, Hiroshi Naganawa, Masa Hamada, Hironobu Iinuma, Tomio Takeuchi, Kayoko S. Tsuchiya, Makoto Hori

Journal:

Year:

2001

File:

PDF, 27 KB

2001

12

ChemInform Abstract: Isolation and Structural Determination of Phepropeptins A, B, C, and D, New Proteasome Inhibitors, Produced by Streptomyces sp.

Ryuichi Sekizawa, Isao Momose, Naoko Kinoshita, Hiroshi Naganawa, Masa Hamada, Yasuhiko Muraoka, Hironobu Iinuma, Tomio Takeuchi

Journal:

Year:

2002

File:

PDF, 25 KB

2002

13

ChemInform Abstract: Tyropeptins A and B, New Proteasome Inhibitors Produced by Kitasatospora sp. MK993-dF2. Part 1. Taxonomy, Isolation, Physicochemical Properties and Biological Activities.

Isao Momose, Ryuichi Sekizawa, Hideki Hashizume, Naoko Kinoshita, Yoshiko Homma, Masa Hamada, Hironobu Iinuma, Tomio Takeuchi

Journal:

Year:

2002

File:

PDF, 26 KB

2002

14

ChemInform Abstract: Tyropeptins A and B, New Proteasome Inhibitors Produced by Kitasatospora sp. MK993-dF2. Part 2. Structure Determination and Synthesis.

Isao Momose, Ryuichi Sekizawa, Sehei Hirosawa, Daishiro Ikeda, Hiroshi Naganawa, Hironobu Iinuma, Tomio Takeuchi

Journal:

Year:

2002

File:

PDF, 27 KB

2002

15

ChemInform Abstract: Some Biological and Biochemical Activities of Resormycin, a Novel Herbicidal Antibiotic.

Masayuki Igarashi, Manabu Kawada, Masa Hamada, Hironobu Iinuma, Hidemi Hayashi, Kayoko Tsuchiya, Makoto Hori

Journal:

Year:

2002

File:

PDF, 25 KB

2002

16

ChemInform Abstract: In vitro and in vivo Antiprotozoal Activities of Bispolides and Their Derivatives.

Kazuhiko Otoguro, Masato Iwatsuki, Aki Ishiyama, Miyuki Namatame, Aki Nishihara-Tsukashima, Seigo Sato, Masahiro Hatsu, Hironobu Iinuma, Seiji Shibahara, Satoshi Nimura, et al. et al.

Journal:

Year:

2010

File:

PDF, 15 KB

2010

17

A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp.

Hideaki Ui, Toshiaki Miyake, Hironobu Iinuma, Masaya Imoto, Seiko Hattori, Masa Hamada, Tomio Takeuchi, Sumio Umezawa, Kazuo Umezawa

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 153 KB

english, 1995

18

Structure-based design of derivatives of tyropeptin A as the potent and selective inhibitors of mammalian 20S proteasome

Isao Momose, Yoji Umezawa, Sehei Hirosawa, Hironobu Iinuma, Daishiro Ikeda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 281 KB

english, 2005

19

The structure of coriolin, a new sesquiterpene antibiotic

Shuji Takahashi, Hironobu Iinuma, Tomohisa Takita, Kenji Maeda, Hamao Umezawa

Journal:

Tetrahedron Letters

Year:

1969

Language:

english

File:

PDF, 180 KB

english, 1969

20

Revised Structure and Stereochemistry of Coriolins

Shuji Takahashi, Hiroshi Naganawa, Hironobu Iinuma, Tomohisa Takita, Kenji Maeda, Hamao Umezawa

Journal:

Tetrahedron Letters

Year:

1971

Language:

english

File:

PDF, 203 KB

english, 1971

21

The structures of coriolin B and C

Shuji Takahashi, Hironobu Iinuma, Tomohisa Takita, Kenji Maeda, Hamao Umezawa

Journal:

Tetrahedron Letters

Year:

1970

Language:

english

File:

PDF, 143 KB

english, 1970

22

Synthesis of anti-rheumatic agent epoxyquinomicin B

Naoki Matsumoto, Hironobu Iinuma, Tsutomu Sawa, Tomio Takeuchi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 190 KB

english, 1998

23

Production of gibberellin-like substance in the embryo of barley during germination

Harugoro Yomo, Hironobu Iinuma

Journal:

Year:

1966

Language:

english

File:

PDF, 328 KB

english, 1966

24

Bispolides, Novel 20-Membered Ring Macrodiolide Antibiotics from Microbispora

Okujo, Noriyuki, Iinuma, Hironobu, George, Annie, Eim, Khor Siew, Li, Tan Lee, Ting, Ng Szu, Jye, Tan Chin, Hotta, Kunimoto, Hatsu, Masahiro, Fukagawa, Yasuo

Journal:

The Journal of Antibiotics

Year:

2007

Language:

english

File:

PDF, 76 KB

english, 2007

25

In vitro and in vivo antiprotozoal activities of bispolides and their derivatives

Otoguro, Kazuhiko, Iwatsuki, Masato, Ishiyama, Aki, Namatame, Miyuki, Nishihara-Tsukashima, Aki, Sato, Seigo, Hatsu, Masahiro, Iinuma, Hironobu, Shibahara, Seiji, Nimura, Satoshi

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 167 KB

english, 2010

26

3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases

Shinichi Koizumi, Yuko Matsushima, Toshiharu Nagatsu, Hironobu Iinuma, Tomio Takeuchi, Hamao Umezawa

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1984

Language:

english

File:

PDF, 557 KB

english, 1984

27

Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice

Sonoko Atsumi, Chisato Nosaka, Hironobu Iinuma, Kazuo Umezawa

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 1.07 MB

english, 1992

28

Inhibition of brain prostaglandin d synthetase and prostaglandin D2 dehydrogenase by some saturated and unsaturated fatty acids

Osama Hiroyoshi, Narumiya Shuh, Hayaishi Osamu, Iinuma Hironobu, Takeuchi Tomio, Umezawa Hamao

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1983

Language:

english

File:

PDF, 888 KB

english, 1983

29

Migracins A and B, new inhibitors of cancer cell migration, produced by Streptomyces sp.

Arai, Yuhei, Iinuma, Hironobu, Ikeda, Yoko, Igarashi, Masayuki, Hatano, Masaki, Kinoshita, Naoko, Ukaji, Tamami, Simizu, Siro, Umezawa, Kazuo

Journal:

The Journal of Antibiotics

Year:

2013

Language:

english

File:

PDF, 693 KB

english, 2013

30

Isolation of a Novel Tyrosine Kinase Inhibitor, Lavendustin A, from Streptomyces griseolavendus

Onoda, Toshihiko, Iinuma, Hironobu, Sasaki, Yumi, Hamada, Masa, Isshiki, Kunio, Naganawa, Hiroshi, Takeuchi, Tomio, Tatsuta, Kuniaki, Umezawa, Kazuo

Journal:

Journal of Natural Products

Year:

1989

Language:

english

File:

PDF, 323 KB

english, 1989

31

Oudenone, a novel tyrosine hydroxylase inhibitor from microbial origin

Ono, Masaji, Okamoto, Masaru, Kawabe, Norio, Umezawa, Hamao, Takeuchi, Tomio, Iinuma, Hironobu, Takahashi, Shuji

Journal:

Journal of the American Chemical Society

Year:

1971

Language:

english

File:

PDF, 256 KB

english, 1971

32

Isolation and Synthesis of Novel Farnesyl Protein Transferase Inhibitors, Valinoctins A and B, from Streptomyces Strain MJ858-NF3

Sekizawa, Ryuichi, Iinuma, Hironobu, Muraoka, Yasuhiko, Naganawa, Hiroshi, Kinoshita, Naoko, Nakamura, Hikaru, Hamada, Masa, Takeuchi, Tomio, Umezawa, Kazuo

Journal:

Journal of Natural Products

Year:

1996

Language:

english

File:

PDF, 222 KB

english, 1996

33

Isolation and Structure Determination of Novel Phosphatidylinositol Kinase Inhibitors, Echiguanines A and B, from Streptomyces sp.

Nishioka, Hiroshi, Sawa, Tsutomu, Nakamura, Hikaru, Iinuma, Hironobu, Ikeda, Daishiro, Sawa, Ryuichi, Naganawa, Hiroshi, Hayashi, Chigusa, Hamada, Masa, Takeuchi, Tomio, Iitaka, Yoichi, Umezawa, Kazuo

Journal:

Journal of Natural Products

Year:

1991

Language:

english

File:

PDF, 302 KB

english, 1991

34

Pholipeptin, a Novel Cyclic Lipoundecapeptide from Pseudomonas fluorescens

Ui, Hideaki, Miyake, Toshiaki, Iinuma, Hironobu, Imoto, Masaya, Naganawa, Hiroshi, Hattori, Seiko, Hamada, Masa, Takeuchi, Tomio, Umezawa, Sumio, Umezawa, Kazuo

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 177 KB

english, 1997

35

Isolation of a novel paxilline analog pyrapaxilline from fungus that inhibits LPS-induced NO production

Matsui, Chino, Ikeda, Yoko, Iinuma, Hironobu, Kushida, Nobuaki, Kunisada, Takao, Simizu, Siro, Umezawa, Kazuo

Journal:

The Journal of Antibiotics

Year:

2014

Language:

english

File:

PDF, 294 KB

english, 2014

36

Synthesis and Activity of Tyropeptin A Derivatives as Potent and Selective Inhibitors of Mammalian 20S Proteasome

MOMOSE, Isao, UMEZAWA, Yoji, HIROSAWA, Sehei, IIJIMA, Masatomi, IINUMA, Hironobu, IKEDA, Daishiro

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

37

Inhibition of Proteasome Activity by Tyropeptin A in PC12 Cells

MOMOSE, Isao, SEKIZAWA, Ryuichi, IINUMA, Hironobu, TAKEUCHI, Tomio

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2002

Language:

english

File:

PDF, 1.54 MB

english, 2002

38

Inhibition of Lysenin-induced Hemolysis by All-E-Lutein Derived from the Plant Dalbergia latifolia

Niwa, Yuki, Matsui, Chino, Sukumwang, Neelanun, Iinuma, Hironobu, Ikeda, Yoko, Koyano, Takashi, Kovitayakorn, Taworn, Simizu, Siro, Umezawa, Kazuo

Journal:

Year:

2012

Language:

english

File:

PDF, 117 KB

english, 2012

39

PRODUCTION OF GIBBERELLIN-LIKE SUBSTANCE IN THE EMBRYO OF BARLEY DURING GERMINATION

H. Jinuma, Harugoro Yomo and Hironobu Iinuma

Journal:

Year:

1966

Language:

english

File:

PDF, 566 KB

english, 1966

40

A New Cytotoxic 2H-Pyran Compound Produced by Acid Treatment of the Fermentation Broth of Streptomyces Sp.

NOSAKA, Chisato, KUNIMOTO, Setsuko, MASUDA, Thoru, OHSONO, Michiyo, IINUMA, Hironobu, TSUCHIDA, Toshio, HAMADA, Masa, TAKEUCHI, Tomio

Journal:

Biological & Pharmaceutical Bulletin

Year:

1999

File:

PDF, 484 KB

1999

41

DIKETOCORIOLIN B, AN ACTIVE DERIVATIVE OF CORIOLIN B PRODUCED BY CORIOLUS CONSORS

TAKEUCHI, TOMIO, TAKAHASHI, SHUJI, IINUMA, HIRONOBU, UMEZAWA, HAMAO

Journal:

The Journal of Antibiotics

Year:

1971

Language:

english

File:

PDF, 611 KB

english, 1971

42

EFFECT OF DIKETOCORIOLIN B ON ANTIBODY FORMATION

ISHIZUKA, MASAAKI, IINUMA, HIRONOBU, TAKEUCHI, TOMIO, UMEZAWA, HAMAO

Journal:

The Journal of Antibiotics

Year:

1972

Language:

english

File:

PDF, 126 KB

english, 1972

43

MONOAMINE OXIDASE INHIBITORS ISOLATED FROM FERMENTED BROTHS

TAKEUCHI, TOMIO, OGAWA, KEIJI, IINUMA, HIRONOBU, SUDA, HIROYUKI, UKITA, KATSUKO, NAGATSU, TOSHIHARU, KATO, MASAAKI, UMEZAWA, HAMAO, TANABE, OSAMU

Journal:

The Journal of Antibiotics

Year:

1973

Language:

english

File:

PDF, 357 KB

english, 1973

44

DOPASTIN, AN INHIBITOR OF DOPAMINE β-HYDROXYLASE

IINUMA, HIRONOBU, TAKEUCHI, TOMIO, KONDO, SHINICHI, MATSUZAKI, MEIKI, UMEZAWA, HAMAO, OHNO, MASAJI

Journal:

The Journal of Antibiotics

Year:

1972

Language:

english

File:

PDF, 234 KB

english, 1972

45

A new antibiotic, calvatic acid.

UMEZAWA, HAMAO, TAKEUCHI, TOMIO, IINUMA, HIRONOBU, ITO, MANABU, ISHIZUKA, MASAAKI, KURAKATA, YASUO, UMEDA, YOSHIHISA, NAKANISHI, YOSHIKUNI, NAKAMURA, TERUYA, OBAYASHI, AKIRA, TANABE, OSAMU

Journal:

The Journal of Antibiotics

Year:

1975

Language:

english

File:

PDF, 1.60 MB

english, 1975

46

Dehydrodicaffeic acid dilactone, an inhibitor of catechol-O-methyl transferase.

KUMADA, YOSHIKI, NAGANAWA, HIROSHI, IINUMA, HIRONOBU, MATSUZAKI, MEIKI, TAKEUCHI, TOMIO, UMEZAWA, HAMAO

Journal:

The Journal of Antibiotics

Year:

1976

Language:

english

File:

PDF, 4.32 MB

english, 1976

47

2-Amino-5-methyl-5-hexenoic acid, a methionine analog produced by Streptomyces sp. MF374-C4.

TAKEUCHI, MIEKO, IINUMA, HIRONOBU, TAKEUCHI, TOMIO, UMEZAWA, HAMAO, SUZUKAKE, KAYOKO, HORI, MAKOTO

Journal:

The Journal of Antibiotics

Year:

1979

Language:

english

File:

PDF, 3.26 MB

english, 1979

48

A new antitumor antibiotic, spergualin: Isolation and antitumor activity.

TAKEUCHI, TOMIO, IINUMA, HIRONOBU, KUNIMOTO, SETSUKO, MASUDA, TORU, ISHIZUKA, MASAAKI, TAKEUCHI, MIEKO, HAMADA, MASA, NAGANAWA, HIROSHI, KONDO, SHINICHI, UMEZAWA, HAMAO

Journal:

The Journal of Antibiotics

Year:

1981

Language:

english

File:

PDF, 1.35 MB

english, 1981

49

Basidalin,a new antibiotic from basidiomycetes.

IINUMA, HIRONOBU, NAKAMURA, HIKARU, NAGANAWI, HIROSHI, MASUDA, TORU, TAKANO, SHUICHI, TAKEUCHI, TOMIO, UMEZAWA, HAMAO, IITAKA, YOICHI, OBAYASHI, AKIRA

Journal:

The Journal of Antibiotics

Year:

1983

Language:

english

File:

PDF, 1.42 MB

english, 1983

50

The total synthesis of spergualin, an antitumor antibiotic.

KONDO, SHINICHI, IWASAWA, HIROYUKI, IKEDA, DAISHIRO, UMEDA, YOSHIHISA, IKEDA, YOKO, IINUMA, HIRONOBU, UMEZAWA, HAMAO

Journal:

The Journal of Antibiotics

Year:

1981

Language:

english

File:

PDF, 1.31 MB

english, 1981